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The brains from mice treated with intranasal GHK-Cu showed a decrease in MCP-1, a marker used to indicate inflammation [33]

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Any disruption in this chain—whether from age-related decline in gastric acid, autoimmune gastritis (pernicious anemia), medications (particularly proton pump inhibitors and metformin), or gastrointestinal surgery—can impair absorption regardless of how much B12 you take orally